Welcome to the website of the PCT

 

Proteome Center Tuebingen (PCT) was founded in 2003 as a part of the Interdepartmental Institute for Cell Biology (IFIZ) and it has since established and applied methods for quantitative analysis of protein expression using state-of-the-art methodology and instrumentation. Since December 2008, the PCT is led by Prof. Boris Macek, who has a teaching assignment at the Faculty of Biology, University of Tuebingen.   

PCT currently employs staff of 10 scientists and support personnel with core expertise in methods of protein analysis, such as different electrophoresis techniques and protein identification by mass spectrometry. Quantitative workflows are mainly based on stable isotope labeling of cells and tissues and measurements of resulting protein digests using state-of-the-art LTQ-Orbitrap mass spectrometry. In addition, PCT possesses considerable infrastructure and expertise in protein/peptide separation technologies based on various analytical HPLC methods, as well as bioinformatic analysis of shot-gun proteomics data.


PCT performs active research in the areas of proteogenomics, phosphoproteomics, quantitative analysis of protein modifications and method development. As a core facility of the University of Tuebingen, the PCT also offers proteomics analyses against a fee.